Description

2'-Hydroxy-3,4,4'-Trimethoxychalcone is a synthetic chalcone derivative, a class of compounds known for their diverse biological activities. This high-purity intermediate is critical for research and development in advanced organic synthesis and pharmaceutical discovery. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for its utility as a key building block.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates targeting inflammation, cancer, and metabolic disorders.
• Biochemical Research: Used as a reference standard or probe compound in pharmacological studies to investigate enzyme inhibition and receptor binding mechanisms.
• Organic Synthesis Building Block: Utilized in the construction of more complex heterocyclic compounds and natural product analogs due to its reactive α,β-unsaturated ketone moiety.
• Agrochemical Development: Explored as a lead structure for developing new plant growth regulators or protective agents.
• Material Science Research: Investigated for potential applications in organic electronics and as a component in advanced polymeric materials.

Basic Information

Product Name	2'-Hydroxy-3,4,4'-Trimethoxychalcone
CAS No.	10493-06-8
Molecular Formula	C₁₈H₁₈O₅
Molecular Weight	314.33 g/mol
Synonyms	2'-Hydroxy-3,4,4'-trimethoxychalcone; (E)-1-(2-Hydroxyphenyl)-3-(3,4,4-trimethoxyphenyl)prop-2-en-1-one; 3,4,4'-Trimethoxy-2'-hydroxychalcone; NSC 407347; Chalcone, 2'-hydroxy-3,4,4'-trimethoxy-; 1-(2-Hydroxyphenyl)-3-(3,4,5-trimethoxyphenyl)-2-propen-1-one
EINECS	Contact for details

Quality Control

Our 2'-Hydroxy-3,4,4'-Trimethoxychalcone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.