Description

Spiro[3.3]heptane-2,6-dicarboxylic acid monomethyl ester is a high-value, multifunctional spirocyclic building block and chiral synthon. This compound matters for its rigid, three-dimensional structure which is instrumental in modulating the physicochemical properties of advanced materials and active pharmaceutical ingredients. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty polymer industries for applications in medicinal chemistry, asymmetric synthesis, and the development of novel functional materials.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Asymmetric Synthesis: Serves as a precursor for chiral ligands, catalysts, and auxiliaries used in stereoselective transformations.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science: Incorporated into polymers and liquid crystals to impart rigidity, thermal stability, and unique optical properties.
• Chemical Biology: Employed as a molecular scaffold or probe in the study of protein-ligand interactions and enzyme mechanisms.
• Academic & Contract Research: A valuable reagent for methodological development and exploration of new chemical space in university and CRO laboratories.

Basic Information

Item	Details
Product Name	Spiro[3.3]heptane-2,6-dicarboxylic Acid Monomethyl Ester
CAS No.	10481-25-1
Molecular Formula	C11H14O4
Molecular Weight	210.23 g/mol
Synonyms	2,6-Bis(methoxycarbonyl)spiro[3.3]heptane; Monomethyl ester of Spiro[3.3]heptane-2,6-dicarboxylic acid; Dimethyl spiro[3.3]heptane-2,6-dicarboxylate (common name check); Spiro[3.3]heptane-2,6-dicarboxylic acid methyl ester; 2,6-Spiroheptanedicarboxylic acid monomethyl ester; CAS 10481-25-1; 2,6-Dicarbomethoxyspiro[3.3]heptane
EINECS	Contact for details

Quality Control

Our Spiro[3.3]heptane-2,6-dicarboxylic acid monomethyl ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (enantiomerically enriched grade available)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.