Description

2-Tolylisocyanide 95 is an organoisocyanide compound, a versatile and reactive building block in synthetic organic chemistry. Its primary value lies in its role as a ligand in transition metal catalysis and as a key precursor in multicomponent reactions for constructing complex heterocycles and pharmaceuticals. This high-purity grade is essential for researchers and process chemists in the fine chemical, agrochemical, and pharmaceutical development sectors who require reliable and consistent starting materials for advanced synthesis.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Catalysis & Ligand Chemistry: Used as a ligand for palladium, rhodium, and other transition metals in cross-coupling and other catalytic reactions.
• Agrochemical Synthesis: Employed in the research and development of new pesticides and herbicides.
• Material Science Research: A precursor for the development of functional polymers and advanced organic materials.
• Multicomponent Reactions (MCRs): A key reactant in Passerini and Ugi-type reactions for the efficient generation of molecular diversity.
• Academic & Industrial R&D: Fundamental reagent for methodological development in synthetic organic chemistry laboratories.

Basic Information

Product Name	2-Tolylisocyanide 95
CAS No.	10468-64-1
Molecular Formula	C8H7N
Molecular Weight	117.15 g/mol
Synonyms	2-Methylphenyl isocyanide; o-Tolyl isocyanide; 2-Tolyl isonitrile; (2-Methylphenyl)isocyanide; Isocyanomethylene-2-methylbenzene; 2-Methylbenzenecarbonitrile; o-Tolylisonitrile; 1-Isocyano-2-methylbenzene
EINECS	Contact for details

Quality Control

Our 2-Tolylisocyanide 95 is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed to confirm identity and assay, with comprehensive testing for key impurities. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed and stored upright. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.