Description

3β-[(Trimethylsilyl)Oxy]-5α-Androstan-17-One is a high-purity steroid derivative, specifically a silyl-protected androstane intermediate. This compound is of significant value in pharmaceutical research and development, serving as a crucial building block for the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs). It is primarily needed by R&D laboratories, pharmaceutical manufacturers, and fine chemical suppliers engaged in the production of hormone therapies, anti-inflammatory agents, and other specialized steroid compounds.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step production of steroidal drugs and hormones.
• Research & Development: Used in academic and industrial laboratories for exploring new synthetic pathways and novel steroid derivatives.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in steroid analysis.
• Process Chemistry: Employed in scale-up and process optimization for the commercial manufacturing of steroid APIs.
• Biochemical Research: Utilized in studies investigating steroid metabolism, receptor binding, and enzymatic activity.

Basic Information

Product Name	3β-[(Trimethylsilyl)Oxy]-5α-Androstan-17-One
CAS No.	10426-95-6
Molecular Formula	C22H38O2Si
Molecular Weight	362.62 g/mol
Synonyms	3β-(Trimethylsilyloxy)-5α-androstan-17-one; 5α-Androstan-17-one, 3-[(trimethylsilyl)oxy]-, (3β)-; 3β-Hydroxy-5α-androstan-17-one trimethylsilyl ether; Androstanolone TMS ether; 3-TMS-androsterone; 3β-TMS-androsterone; 5α-Androsterone 3-TMS ether
EINECS	Contact for details

Quality Control

Our 3β-[(Trimethylsilyl)Oxy]-5α-Androstan-17-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis to ensure compliance with research and pharmaceutical intermediate grade standards. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.