Description

2,3,5,6-Tetrachloropyridine-4-Thiol is a versatile and highly functionalized heterocyclic building block, valued for its unique reactivity as a thiol-substituted, perchlorinated pyridine derivative. This compound is a critical intermediate in the synthesis of advanced agrochemicals and pharmaceuticals, where its structure enables the introduction of sulfur-containing functional groups. It is primarily sought by R&D chemists and process development teams in the agrochemical, pharmaceutical, and specialty chemical industries for creating novel active ingredients and complex molecules.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of modern herbicides, fungicides, and insecticides, leveraging its sulfur and chlorine atoms for bioactivity.
• Pharmaceutical Building Block: Used in medicinal chemistry research for the development of new drug candidates, particularly those requiring a thiolated pyridine core.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and material science.
• Polymer Modification: Can be utilized to introduce functional groups into polymer chains to alter material properties.
• Organic Synthesis Reagent: Employed in various organic transformations where a reactive thiol and electron-deficient pyridine ring are required.

Basic Information

Product Name	2,3,5,6-Tetrachloropyridine-4-Thiol
CAS No.	10351-06-1
Molecular Formula	C5HCl4NS
Molecular Weight	248.94 g/mol
Synonyms	4-Pyridinethiol, 2,3,5,6-tetrachloro-; Tetrachloro-4-pyridinethiol; 2,3,5,6-Tetrachloro-4-mercaptopyridine; 2,3,5,6-Tetrachloro-4-pyridinethiol; 4-Mercapto-2,3,5,6-tetrachloropyridine; 2,3,5,6-Tetrachloro-4-thiopyridinol; 10351-06-1; NSC 403079
EINECS	Contact for details

Quality Control

Our 2,3,5,6-Tetrachloropyridine-4-Thiol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. For long-term storage, keep at 2-8°C under an inert atmosphere. This material is moisture-sensitive (hygroscopic) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.