Description

4-Methoxyphenyl Isocyanide is a versatile aromatic isocyanide building block, essential for the synthesis of complex heterocycles and functional materials. Its high reactivity as an isocyanide makes it a critical reagent in multicomponent reactions, enabling efficient construction of diverse molecular scaffolds. This compound is primarily sought by research institutions and industrial R&D departments focused on pharmaceutical development, agrochemical discovery, and advanced material science.

Application

• Pharmaceutical Intermediate: A key synthon in the preparation of heterocyclic compounds via Passerini and Ugi multicomponent reactions for drug discovery.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its ability to form complex nitrogen-containing structures.
• Material Science Research: Employed in the synthesis of functional polymers, ligands for catalysis, and metal-organic frameworks (MOFs).
• Chemical Biology: Serves as a bioorthogonal reagent for labeling and modifying biomolecules in probe development.
• Catalyst Ligand Precursor: Utilized to create specialized isocyanide-based ligands for transition metal catalysis.
• Academic & Industrial R&D: Fundamental building block for methodological development in organic synthesis and medicinal chemistry.

Basic Information

Product Name	4-Methoxyphenyl Isocyanide
CAS No.	10349-38-9
Molecular Formula	C8H7NO
Molecular Weight	133.15 g/mol
Synonyms	p-Methoxyphenyl isocyanide; 1-Isocyano-4-methoxybenzene; 4-Methoxyphenylisocyanide; 4-Methoxybenzenisocyanid; 4-Methoxyphenyl isonitrile; p-Methoxybenzene isocyanide; p-Methoxyphenylisonitrile; (4-Methoxyphenyl)isocyanide
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity (typically by GC or HPLC), appearance, and other critical parameters are available upon request. We adhere to strict in-house quality management protocols to guarantee supply reliability for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its light-sensitive and highly volatile nature, it is recommended to store the material at 2-8°C under an inert atmosphere for long-term stability. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.