Description

Benzyl Isocyanide is a versatile organic building block characterized by its reactive isocyanide functional group. This compound is essential for facilitating the synthesis of complex heterocycles and bioactive molecules through multicomponent reactions. It is a critical reagent for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to create novel molecular architectures efficiently.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of nitrogen-containing heterocycles, such as imidazoles and oxazoles, which are core structures in many active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its reactivity to introduce functional diversity into lead compounds.
• Material Science Research: Employed in the creation of specialized polymers, ligands for catalysis, and metal-organic frameworks (MOFs) due to its strong coordinating ability.
• Multicomponent Reaction (MCR) Chemistry: Serves as a fundamental component in Passerini and Ugi reactions, enabling the rapid, one-pot assembly of complex amides and peptide-like structures.
• Ligand in Catalysis: Acts as a ligand for transition metals, modifying catalyst properties in various cross-coupling and oxidation reactions.
• Chemical Biology Probes: Utilized in bioorthogonal chemistry and activity-based protein profiling to study biological processes.

Basic Information

Product Name	Benzyl Isocyanide
CAS No.	10340-91-7
Molecular Formula	C8H7N
Molecular Weight	117.15 g/mol
Synonyms	Benzylisonitrile; Isocyanomethane, phenyl-; Phenylmethyl isocyanide; (Isocyanomethyl)benzene; α-Isocyanotoluene; Benzyl carbylamine; NSC 9376; Benzenemethyl isocyanide
EINECS	233-746-7

Quality Control

Our Benzyl Isocyanide is manufactured under strict quality management systems. Every batch is subjected to rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed and upright to prevent leakage and evaporation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.