Description

(S)-Methyl 2,3-Dihydroxypropanoate is a high-purity chiral building block and synthetic intermediate of significant importance in advanced organic synthesis. This compound matters because its stereochemistry and bifunctional diol ester structure make it a versatile precursor for pharmaceuticals, fine chemicals, and specialty materials. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and flavor & fragrance industries for developing enantiomerically pure products.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, cardiovascular, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Flavor and Fragrance Industry: Serves as a precursor for the synthesis of natural flavor compounds and aroma chemicals.
• Polymer Chemistry: Monomer or co-monomer for creating functionalized polyesters and biodegradable polymers with tailored properties.
• Ligand and Catalyst Preparation: Building block for synthesizing chiral ligands used in asymmetric catalysis.
• Bioconjugation and Linker Chemistry: Utilized in bioconjugation techniques and as a spacer or linker molecule in prodrug design.

Basic Information

Product Name	(S)-Methyl 2,3-Dihydroxypropanoate
CAS No.	10303-88-5
Molecular Formula	C4H8O4
Molecular Weight	120.10 g/mol
Synonyms	(S)-Methyl 2,3-Dihydroxypropionate; (S)-Methyl Glycerate; (S)-Methyl 2,3-Dihydroxypropanoic Acid Ester; (S)-2,3-Dihydroxypropanoic Acid Methyl Ester; (S)-Glyceric Acid Methyl Ester; Methyl (S)-Glycerate; (S)-(-)-Methyl Glycerate; L-Methyl Glycerate
EINECS	233-683-5

Quality Control

Our (S)-Methyl 2,3-Dihydroxypropanoate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. We provide comprehensive quality assurance, with specifications typically meeting or exceeding standards for research and cGMP manufacturing. Certificates of Analysis (COA) detailing identity, purity (HPLC/GC), chiral purity, and impurity profiles are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged operations to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.