Description

trans-4-(Piperidin-1-yl)tetrahydrofuran-3-ol is a versatile chiral building block and intermediate of significant importance in advanced organic synthesis. Its value lies in its unique molecular scaffold, which combines a piperidine ring with a functionalized tetrahydrofuran moiety, enabling the construction of complex pharmacophores. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of potential drug candidates, particularly those targeting neurological and metabolic disorders.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides due to its bioactive heterocyclic structure.
• Ligand and Catalyst Synthesis: Employed in the preparation of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Acts as a building block for creating complex molecules used in flavors, fragrances, and advanced materials science.
• Academic & R&D: Utilized in university and corporate research laboratories for methodological studies in synthetic organic chemistry.

Basic Information

Product Name	trans-4-(Piperidin-1-yl)tetrahydrofuran-3-ol
CAS No.	10295-96-2
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	trans-4-Piperidin-1-yl-tetrahydrofuran-3-ol; 3-Piperidino-4-hydroxy-tetrahydrofuran; 3-Hydroxy-4-piperidinotetrahydrofuran; 4-(1-Piperidinyl)-3-tetrahydrofuranol; 4-(N-Piperidino)-3-hydroxy-tetrahydrofuran; 3-Hydroxy-4-(piperidin-1-yl)tetrahydrofuran; THF derivative 10295-96-2; 4-Piperidin-1-yloxolan-3-ol
EINECS	Contact for details

Quality Control

Our trans-4-(Piperidin-1-yl)tetrahydrofuran-3-ol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% de (trans isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.