Description

Diethyl 2-(1H-Indol-3-Ylmethylidene)Propanedioate is a versatile indole-based chemical intermediate with a conjugated malonate ester structure. This compound is valued for its role as a key building block in the synthesis of complex heterocyclic molecules and active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing new compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel indole alkaloids and potential drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new plant growth regulators or pesticides that leverage the indole scaffold's bioactivity.
• Organic Synthesis Building Block: Serves as a Michael acceptor or a dienophile in cycloaddition reactions for constructing complex polycyclic frameworks in fine chemistry.
• Material Science Research: Investigated as a monomer or precursor for organic semiconductors and functional materials due to its extended π-conjugation.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized indole-based colorants and fluorescent markers.

Basic Information

Product Name	Diethyl 2-(1H-Indol-3-Ylmethylidene)Propanedioate
CAS No.	10184-96-0
Molecular Formula	C₁₆H₁₇NO₄
Molecular Weight	287.31 g/mol
Synonyms	Diethyl (E)-2-(1H-Indol-3-ylmethylene)malonate; Diethyl (1H-Indol-3-ylmethylene)malonate; Propanedioic acid, 2-(1H-indol-3-ylmethylene)-, diethyl ester; 3-Carbethoxy-2-(indol-3-ylmethylene)malonic acid diethyl ester; (E)-Diethyl 2-(1H-indol-3-ylmethylene)malonate; Ethyl 3-(1H-indol-3-yl)-2-cyanoacrylate precursor (related compound); Indole-3-carboxaldehyde diethyl malonate derivative
EINECS	Contact for details

Quality Control

Our Diethyl 2-(1H-Indol-3-Ylmethylidene)Propanedioate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, physical characteristics, and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat sources and incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.