Description

2-Chloro-6-Methyl-5-Phenylnicotinonitrile is a versatile and high-value pharmaceutical intermediate and chemical building block. This compound is critical for the synthesis of complex molecules, particularly in medicinal chemistry and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those with nicotinonitrile or pyridine cores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a precursor for the development of advanced organic materials, including ligands for catalysis and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a versatile scaffold for creating molecular probes and tool compounds in biochemical research.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Chloro-6-Methyl-5-Phenylnicotinonitrile
CAS No.	10176-63-3
Molecular Formula	C13H9ClN2
Molecular Weight	228.68 g/mol
Synonyms	5-Phenyl-2-chloro-6-methylnicotinonitrile; 2-Chloro-5-phenyl-6-methyl-3-cyanopyridine; 3-Cyano-2-chloro-6-methyl-5-phenylpyridine; 2-Chloro-6-methyl-5-phenyl-3-pyridinecarbonitrile; Nicotinonitrile, 2-chloro-6-methyl-5-phenyl-; 2-Chloro-6-methyl-5-phenylpyridine-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Methyl-5-Phenylnicotinonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for all shipments, supporting your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.