Description

Phosphoramide Mustard is a specialized alkylating agent of significant interest in advanced chemical synthesis and research. This compound matters for its role as a key intermediate in the development of targeted therapeutic agents and biochemical probes. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on oncology research and novel drug discovery.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of experimental chemotherapeutic agents and prodrugs.
• Biochemical Research: Used as a model alkylating agent in studies of DNA cross-linking mechanisms and cellular apoptosis.
• Anticancer Agent Development: Serves as a core structural component for creating novel targeted cancer therapies.
• Academic & Contract Research: Employed in university and CRO settings for investigating nitrogen mustard pharmacology and structure-activity relationships (SAR).
• Reference Standard: Utilized as an analytical standard in quality control and method development for related pharmaceutical compounds.

Basic Information

Product Name	Phosphoramide Mustard
CAS No.	10159-53-2
Molecular Formula	C5H13Cl2N2O2P
Molecular Weight	235.05 g/mol
Synonyms	N,N-Bis(2-chloroethyl)phosphorodiamidic Acid; Cyclophosphamide Metabolite; NSC 69971; Phosphorodiamidic Acid, N,N-Bis(2-chloroethyl)-; 2-[Bis(2-chloroethyl)amino]-1,3,2λ⁵-oxazaphospholidine 2-Oxide (tautomer); Nor-Nitrogen Mustard Phosphoramide; PM
EINECS	Contact for details

Quality Control

Our Phosphoramide Mustard is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment to support your research and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.