Description

(±)-α-[(Ethylamino)Methyl]-m-Hydroxybenzyl Alcohol CAS NO 10128-36-6 is a versatile chiral amino alcohol derivative, serving as a critical intermediate in advanced organic synthesis. Its molecular structure, featuring both amino and phenolic hydroxyl groups, makes it a valuable building block for constructing complex molecules with high pharmacological relevance. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly for applications in asymmetric synthesis and the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of β-adrenergic blocking agents (β-blockers) and other cardiovascular drugs.
• Asymmetric Catalyst Ligand Precursor: Used in the preparation of chiral ligands for metal-catalyzed asymmetric reactions, enhancing enantioselectivity.
• Fine Chemical Synthesis: Building block for the production of complex agrochemicals, dyes, and specialty polymers requiring specific stereochemistry.
• Academic & Industrial R&D: Serves as a reference standard and starting material in medicinal chemistry research for exploring new therapeutic pathways.
• Resolution Agent: Potential use in the chiral resolution of racemic mixtures due to its own chiral centers.

Basic Information

Product Name	(±)-α-[(Ethylamino)Methyl]-m-Hydroxybenzyl Alcohol
CAS No.	10128-36-6
Molecular Formula	C11H17NO2
Molecular Weight	195.26 g/mol
Synonyms	1-(3-Hydroxyphenyl)-2-(ethylamino)propan-1-ol; (±)-Ethylnorepinephrine; (±)-Ethylnoradrenaline; DL-α-[(Ethylamino)methyl]-3-hydroxybenzyl alcohol; 3-Hydroxy-α-[(ethylamino)methyl]benzenemethanol; N-Ethylnorepinephrine; N-Ethylarterenol; (±)-N-Ethylnoradrenaline
EINECS	Contact for details

Quality Control

Our production of (±)-α-[(Ethylamino)Methyl]-m-Hydroxybenzyl Alcohol adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent determination, to ensure it meets the high standards required for pharmaceutical R&D and fine chemical synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformance to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	Specification available upon request
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.