Description

Rotundine is a naturally occurring isoquinoline alkaloid known for its significant pharmacological activity. This high-purity compound is valued for its role as a key intermediate in advanced pharmaceutical synthesis and research. It is primarily utilized by manufacturers and research institutions in the pharmaceutical, biotechnology, and fine chemical sectors.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs) targeting the central nervous system.
• Neurological Research: Used in preclinical studies to investigate its effects on neurotransmitter systems and potential therapeutic applications.
• Analytical Reference Standard: Serves as a high-purity standard for quality control and method development in analytical laboratories (HPLC, GC-MS).
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex organic molecules and other specialized alkaloids.
• Biochemical Research: Utilized in studies exploring natural product biosynthesis and enzyme inhibition.

Basic Information

Product Name	Rotundine
CAS No.	10097-84-4
Molecular Formula	C21H25NO4
Molecular Weight	355.43 g/mol
Synonyms	L-Tetrahydropalmatine; Gindarine; Rotundin; NSC 15760; (S)-Canadine; (S)-Tetrahydropalmatine; 5,8,13,13a-Tetrahydro-2,3,9,10-tetramethoxy-6H-dibenzo[a,g]quinolizine; 2,3,9,10-Tetramethoxytetrahydroprotoberberine
EINECS	Contact for details

Quality Control

Our Rotundine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP standards where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical and research customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.