Description

4-[[Bis(2-Chloroethyl)Amino]Methyl]-1,2-Dihydro-1,5-Dimethyl-2-Phenyl-3H-Pyrazol-3-One is a specialized nitrogen mustard derivative with a pyrazolone core, representing a high-value synthetic intermediate in advanced organic synthesis. Its molecular architecture, featuring a bis(2-chloroethyl)amino group, makes it a critical precursor for constructing complex pharmacologically active molecules and targeted chemical probes. This compound is primarily sought by research institutions and pharmaceutical development laboratories engaged in medicinal chemistry, anticancer agent discovery, and the synthesis of novel alkylating agents.

Application

• Pharmaceutical Intermediate: Key building block in the research and development of potential anticancer agents and alkylating chemotherapeutic compounds.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for synthesizing novel bioactive molecules targeting specific enzymes or cellular pathways.
• Biochemical Tool Development: Employed in the creation of chemical probes for studying DNA alkylation, apoptosis mechanisms, and cell signaling.
• Organic Synthesis: Serves as a versatile intermediate for introducing the nitrogen mustard pharmacophore into more complex molecular architectures.
• Academic & Industrial R&D: Utilized in exploratory research for developing new therapeutic modalities and studying structure-activity relationships (SAR).

Basic Information

Product Name	4-[[Bis(2-Chloroethyl)Amino]Methyl]-1,2-Dihydro-1,5-Dimethyl-2-Phenyl-3H-Pyrazol-3-One
CAS No.	10070-94-7
Molecular Formula	C₁₆H₂₁Cl₂N₃O
Molecular Weight	342.26 g/mol
Synonyms	1,2-Dihydro-1,5-dimethyl-2-phenyl-4-[[bis(2-chloroethyl)amino]methyl]-3H-pyrazol-3-one; 4-[[Bis(2-chloroethyl)amino]methyl]-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one; 4-(Bis(2-chloroethyl)aminomethyl)-1,5-dimethyl-2-phenylpyrazol-3-one; 1,5-Dimethyl-2-phenyl-4-[bis(2-chloroethyl)aminomethyl]-1,2-dihydropyrazol-3-one; Nitrogen mustard pyrazolone derivative; Pyrazolone mustard intermediate
EINECS	Contact for details

Quality Control

Every batch of 4-[[Bis(2-Chloroethyl)Amino]Methyl]-1,2-Dihydro-1,5-Dimethyl-2-Phenyl-3H-Pyrazol-3-One is manufactured and analyzed under strict quality management protocols to ensure identity, purity, and consistency for research applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing comprehensive analytical results, including assay purity and impurity profiles, are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.