Description

(-)-4,6'-Dimethoxy-6-Methyl-3,4'-Dioxospiro[Benzofuran-2(3H),1'-[2,5]Cyclohexadiene]-2'-Carboxylic Acid Methyl Ester is a complex spirocyclic organic compound with a unique molecular architecture, making it a valuable advanced intermediate for sophisticated chemical synthesis. This compound matters for its role as a critical chiral building block in the research and development of novel active pharmaceutical ingredients (APIs) and other high-value fine chemicals. It is primarily needed by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers focused on creating complex molecules with specific stereochemistry.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of novel drug candidates, particularly in therapeutic areas requiring complex heterocyclic structures.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where its spirocyclic core can contribute to unique modes of action.
• Material Science: Investigated as a monomer or building block for creating specialized polymers with tailored optical or electronic properties.
• Academic & Industrial R&D: Employed in methodological chemistry research for studying spiroannulation reactions and developing new synthetic pathways.
• Fine Chemical Synthesis: Acts as a high-value intermediate for producing other complex esters, lactones, and functionalized benzofuran derivatives.

Basic Information

Product Name	(-)-4,6'-Dimethoxy-6-Methyl-3,4'-Dioxospiro[Benzofuran-2(3H),1'-[2,5]Cyclohexadiene]-2'-Carboxylic Acid Methyl Ester
CAS No.	1900-29-4
Molecular Formula	C19H18O7
Molecular Weight	358.34 g/mol
Synonyms	Methyl (6S)-4,6'-dimethoxy-6-methyl-3,4'-dioxospiro[1-benzofuran-2,1'-cyclohexa-2,5-diene]-2'-carboxylate; (-)-Methyl 4,6'-dimethoxy-6-methyl-3,4'-dioxospiro[benzofuran-2(3H),1'-[2,5]cyclohexadiene]-2'-carboxylate; Spiro[benzofuran-2(3H),1'-[2,5]cyclohexadiene]-2'-carboxylic acid, 4,6'-dimethoxy-6-methyl-3,4'-dioxo-, methyl ester, (6S)-; 1900-29-4; (6S)-4,6'-Dimethoxy-6-methyl-3,4'-dioxospiro[benzofuran-2(3H),1'-[2,5]cyclohexadiene]-2'-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our (-)-4,6'-Dimethoxy-6-Methyl-3,4'-Dioxospiro[Benzofuran-2(3H),1'-[2,5]Cyclohexadiene]-2'-Carboxylic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound should be handled as a moisture-sensitive material. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.