Description

1-Chloro-4-Isocyanobenzene is a versatile aromatic isocyanate building block of significant importance in advanced organic synthesis. Its value lies in the dual reactivity of the isocyanate group and the halogen substituent, enabling the construction of complex heterocyclic and polymeric structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries seeking to develop novel active ingredients and high-performance materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of urea and carbamate derivatives, which are core structures in various drug candidates, including kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Used to construct herbicidal and pesticidal compounds, particularly those containing phenylurea or anilide moieties.
• Polymer & Resin Production: Serves as a monomer or cross-linking agent in the manufacture of polyurethanes, polyureas, and other specialty polymers with tailored properties.
• Chemical Research & Development: A valuable reagent for introducing the isocyanophenyl group into molecules for material science and medicinal chemistry research.
• Dye & Pigment Manufacturing: Intermediate in the production of certain high-performance pigments and colorants.

Basic Information

Product Name	1-Chloro-4-Isocyanobenzene
CAS No.	1885-81-0
Molecular Formula	C7H4ClNO
Molecular Weight	153.57 g/mol
Synonyms	4-Chlorophenyl isocyanate; p-Chlorophenyl isocyanate; Isocyanic acid, 4-chlorophenyl ester; 1-Isocyanato-4-chlorobenzene; 4-Chlorophenyl isocyanate; 4-Chloro-1-isocyanatobenzene; NSC 406119
EINECS	217-540-3

Quality Control

Our 1-Chloro-4-Isocyanobenzene is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including assay by GC or HPLC, identity confirmation (IR, NMR), and impurity profiling to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its highly volatile nature and reactivity, keep away from moisture, strong bases, and heat sources. Containers should be kept tightly sealed when not in use to prevent moisture ingress and vapor release.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.