Description

4-Nitrophenyl Formate is a specialized organic ester compound, recognized for its utility as a reactive intermediate and protecting group in advanced synthetic chemistry. Its value lies in its ability to act as a formylating agent or a precursor for the controlled release of active species under specific conditions. This product is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries engaged in the development of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly where a protected formyl group is required.
• Peptide Synthesis: Used as a formyl donor or protecting group reagent in solid-phase and solution-phase peptide chemistry.
• Agrochemical Research: Serves as a precursor in the development of new herbicides, fungicides, and plant growth regulators.
• Cross-coupling Reactions: Employed in palladium-catalyzed and other metal-mediated coupling reactions to introduce functional groups.
• Polymer Chemistry: Acts as a monomer or modifying agent in the production of specialty polymers with tailored properties.
• Bioconjugation: Utilized for labeling and modifying biomolecules such as proteins and nucleic acids for diagnostic applications.
• Chemical Biology Probes: Integral in the design and synthesis of activity-based probes for studying enzyme function.

Basic Information

Product Name	4-Nitrophenyl Formate
CAS No.	1865-01-6
Molecular Formula	C7H5NO4
Molecular Weight	167.12 g/mol
Synonyms	p-Nitrophenyl Formate; Formic Acid 4-Nitrophenyl Ester; 4-Nitrophenyl Methanoate; p-Nitrophenyl Formiate; 4-Nitro-phenyl Formate; 4-Nitrophenol Formate; NSC 403119; 4-Nitro Phenol Formic Acid Ester
EINECS	217-468-9

Quality Control

Our 4-Nitrophenyl Formate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure the container is kept tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.