Description

n-Tfa-L-Methionine Methyl Ester is a protected derivative of the essential amino acid L-methionine, specifically designed for advanced peptide synthesis and pharmaceutical research. This compound is crucial for introducing methionine residues into peptide chains while preventing unwanted side reactions during the coupling process. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic peptides and APIs.

Application

• Peptide Synthesis: A key building block (amino acid derivative) in solid-phase and solution-phase peptide synthesis (SPPS).
• Pharmaceutical Intermediates: Used in the research and production of peptide-based active pharmaceutical ingredients (APIs).
• Bioconjugation: Serves as a reagent for modifying proteins or other biomolecules.
• Chemical Biology Research: Employed in studies involving amino acid metabolism, protein engineering, and probe development.
• Fine Chemical Production: Acts as a chiral synthon or intermediate in the synthesis of complex organic molecules.

Basic Information

Product Name	n-Tfa-L-Methionine Methyl Ester
CAS No.	1830-73-5
Molecular Formula	C9H15F3NO4S
Molecular Weight	290.28 g/mol
Synonyms	L-Methionine, N-(trifluoroacetyl)-, methyl ester; Methyl N-(trifluoroacetyl)-L-methioninate; N-[(Trifluoroacetyl)-L-methionine methyl ester; N-Trifluoroacetyl-L-methionine methyl ester; TFA-L-Met-OMe; Trifluoroacetyl-L-methionine methyl ester; Methyl (2S)-2-[(2,2,2-trifluoroacetyl)amino]-4-(methylsulfanyl)butanoate
EINECS	Contact for details

Quality Control

Our n-Tfa-L-Methionine Methyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for pharmaceutical research and peptide synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is sensitive to strong acids and organic solvents; keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.