Description

Trifluoroacetic Acid p-Tolyl Ester is a specialized fluorinated organic ester derived from trifluoroacetic acid and p-cresol. This compound is valued for its role as a versatile building block and reagent in advanced organic synthesis, particularly where the introduction of a trifluoroacetyl group or a protected phenolic moiety is required. It is primarily used by pharmaceutical, agrochemical, and specialty chemical manufacturers engaged in the development of complex molecules.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of active pharmaceutical ingredients (APIs), especially for introducing trifluoroacetyl protecting groups.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides that benefit from fluorinated chemical backbones.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated components in electronic display and lighting materials.
• Polymer Modification: Employed to incorporate fluorine into polymer chains, enhancing material properties like chemical resistance and stability.
• Organic Synthesis Reagent: Acts as an acylating agent or a starting material for various fluorination reactions in research and development laboratories.
• Dye and Pigment Manufacturing: Utilized in the synthesis of specialized fluorinated dyes and colorants.

Basic Information

Product Name	Trifluoroacetic Acid p-Tolyl Ester
CAS No.	1813-29-2
Molecular Formula	C9H7F3O2
Molecular Weight	204.15 g/mol
Synonyms	p-Tolyl Trifluoroacetate; 4-Methylphenyl Trifluoroacetate; Trifluoroacetic Acid 4-Methylphenyl Ester; α,α,α-Trifluoro-p-cresyl Acetate; 4-Methylphenyl Trifluoroethanoate; TFA p-Tolyl Ester; p-Cresyl Trifluoroacetate; 4-(Trifluoroacetoxy)toluene
EINECS	Contact for details

Quality Control

Our Trifluoroacetic Acid p-Tolyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for use in fine chemical synthesis. Certificates of Analysis (COA) with detailed specifications from GC, HPLC, and NMR are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its nature as a strong acid/organic solvent and high volatility, ensure containers are sealed when not in use and stored away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	≤ 2.0% total

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.