Description

Acetic Acid, 2,2,2-Trifluoro-, 3-Nitrophenyl Ester is a specialized fluorinated aromatic ester, a high-value intermediate for advanced chemical synthesis. Its unique structure, combining a trifluoroacetyl group with a nitrophenyl moiety, makes it a critical building block for introducing both fluorine and aromatic nitro functionalities. This compound is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical sectors, where it is used to create novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly for central nervous system (CNS) agents and anti-inflammatory compounds.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the trifluoromethyl group improves metabolic stability and lipophilicity.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials, enhancing performance and stability.
• Polymer Modification: Employed to introduce fluorinated aromatic esters into polymer chains, altering surface properties and chemical resistance.
• Organic Synthesis Reagent: Acts as a versatile acylating agent in research laboratories for the selective modification of amines and alcohols under mild conditions.
• Dye & Pigment Intermediate: Utilized in the production of specialized nitro- and fluoro-containing colorants with unique spectral properties.

Basic Information

Product Name	Acetic Acid, 2,2,2-Trifluoro-, 3-Nitrophenyl Ester
CAS No.	1737-40-2
Molecular Formula	C8H4F3NO4
Molecular Weight	235.12 g/mol
Synonyms	3-Nitrophenyl trifluoroacetate; Trifluoroacetic acid 3-nitrophenyl ester; 3-Nitrophenyl 2,2,2-trifluoroacetate; m-Nitrophenyl trifluoroacetate; 3-Nitrofenyltrifluoroacetát; 2,2,2-Trifluoroacetic Acid 3-Nitrophenyl Ester; α,α,α-Trifluoroacetic Acid m-Nitrophenyl Ester; NSC 404087
EINECS	217-086-6

Quality Control

Our production of Acetic Acid, 2,2,2-Trifluoro-, 3-Nitrophenyl Ester adheres to stringent quality management protocols. Every batch is characterized and tested to ensure high chemical purity and consistency, meeting the exacting standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by GC/HPLC), and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment in a fume hood.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.