Description

Trifluoroacetic Acid o-Tolyl Ester is a specialized fluorinated organic ester derived from trifluoroacetic acid and o-cresol. This compound serves as a valuable building block and reagent in advanced synthetic chemistry, particularly where the introduction of a trifluoroacetyl group or a protected phenolic moiety is required. It is primarily utilized by pharmaceutical intermediates, agrochemical, and specialty chemical manufacturers for research, process development, and production.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring fluorinated aromatic structures.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the trifluoromethyl group enhances biological activity and stability.
• Organic Synthesis Reagent: Acts as a trifluoroacetylating agent or a protecting group for phenolic hydroxyl groups in complex multi-step organic syntheses.
• Liquid Crystal & Electronic Chemicals: Serves as a precursor in the manufacturing of fluorinated compounds for electronic applications and advanced material science.
• Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and novel fluorinated compounds.
• Dye & Pigment Industry: Used in the synthesis of specialized fluorinated dyes and pigments that offer unique properties like enhanced light fastness.

Basic Information

Product Name	Trifluoroacetic Acid o-Tolyl Ester
CAS No.	1736-10-3
Molecular Formula	C9H7F3O2
Molecular Weight	204.15 g/mol
Synonyms	o-Tolyl Trifluoroacetate; 2-Methylphenyl Trifluoroacetate; Trifluoroacetic Acid 2-Methylphenyl Ester; 2-(Trifluoroacetoxy)toluene; o-Cresyl Trifluoroacetate; TFA o-Tolyl Ester; α,α,α-Trifluoro-o-cresyl acetate
EINECS	217-085-6

Quality Control

Our Trifluoroacetic Acid o-Tolyl Ester is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, GC, and NMR to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and we can support compliance with relevant regulatory frameworks upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from heat sources and incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability. The compound is moisture-sensitive; keep container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Total impurities ≤ 2.0%
Density (at 20°C)	~1.25 g/cm³
Refractive Index (n20D)	~1.420 - 1.430

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.