Description

6-Bromo-1,4-Dioxaspiro[4.5]Decane is a versatile brominated spirocyclic ketal, serving as a crucial protected intermediate in advanced organic synthesis. Its value lies in providing a reactive bromine handle on a rigid, oxygenated framework, enabling selective functionalization for building complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to construct key fragments for active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of spirocyclic drug candidates, including potential central nervous system (CNS) agents and other bioactive molecules.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require a halogenated, rigid backbone for optimal activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized phosphine or nitrogen-based ligands used in asymmetric catalysis.
• Material Science Monomer: Potential monomer for synthesizing polymers with unique thermal and mechanical properties due to its spirocyclic structure.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Negishi) and nucleophilic substitution reactions to introduce the cyclohexanone moiety in a protected form.
• Fragrance and Flavor Chemistry: Intermediate for the synthesis of complex musk and other specialty aroma chemicals.

Basic Information

Product Name	6-Bromo-1,4-Dioxaspiro[4.5]Decane
CAS No.	1728-15-0
Molecular Formula	C9H15BrO2
Molecular Weight	235.12 g/mol
Synonyms	6-Bromospiro[1,3-dioxolane-2,1'-cyclohexane]; 6-Bromo-1,4-dioxaspiro[4.5]decane; 2-(4-Bromocyclohexyl)-1,3-dioxolane; 4-Bromocyclohexanone ethylene ketal; Bromocyclohexanone ethylene ketal; 6-Bromocyclohexanone ethylene ketal; 1,4-Dioxaspiro[4.5]decane, 6-bromo-
EINECS	217-045-9

Quality Control

Our 6-Bromo-1,4-Dioxaspiro[4.5]Decane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.