Description

4-Trifluoroacetyl-3-Methyl-1-Phenyl-5-Pyrazolone is a high-purity, specialized pyrazolone derivative featuring a reactive trifluoroacetyl group. This compound matters as a versatile and critical building block in advanced organic synthesis, enabling the introduction of fluorine-containing motifs which are highly sought after for their ability to modulate the physicochemical properties of target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of fluorinated drug candidates, particularly in developing molecules with enhanced metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides where the trifluoromethyl group can improve biological activity and environmental persistence.
• Coordination Chemistry & Chelating Agent: Acts as an effective ligand for metal ions, useful in the preparation of catalysts and in analytical chemistry for metal extraction and detection.
• Material Science Research: Employed in the development of advanced organic materials, including polymers and liquid crystals, where fluorine incorporation can alter electronic properties and stability.
• Fluorine Chemistry Building Block: Provides a convenient source of the -COCF3 moiety for introducing fluorinated ketone or heterocyclic structures in complex molecule assembly.

Basic Information

Product Name	4-Trifluoroacetyl-3-Methyl-1-Phenyl-5-Pyrazolone
CAS No.	1691-93-6
Molecular Formula	C12H9F3N2O2
Molecular Weight	270.21 g/mol
Synonyms	1-Phenyl-3-methyl-4-trifluoroacetyl-5-pyrazolone; 3-Methyl-1-phenyl-4-(trifluoroacetyl)-2-pyrazolin-5-one; 4-(Trifluoroacetyl)-3-methyl-1-phenyl-2-pyrazolin-5-one; TTA; HTTA; thenoyltrifluoroacetone (Note: often used for thienyl analog, but this phenyl variant is closely related); 4-Trifluoroacetyl-3-methyl-1-phenyl-5-pyrazolone; 1-Phenyl-3-methyl-4-trifluoroacetylpyrazol-5-one
EINECS	Contact for details

Quality Control

Our 4-Trifluoroacetyl-3-Methyl-1-Phenyl-5-Pyrazolone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.