Description

3-Bromo-4-Nitropyridine n-Oxide is a versatile and highly functionalized heterocyclic building block. This compound is critical for advanced organic synthesis, particularly in the development of complex molecules for pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and life sciences industries for constructing novel nitrogen-containing scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing complex pyridine or pyridine N-oxide cores.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides where the nitropyridine moiety imparts specific biological activity.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the research and development of advanced organic electronic materials and functional polymers.
• Cross-Coupling Reactions: The bromo substituent makes it a suitable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to create more complex biaryl structures.
• Nucleophilic Aromatic Substitution: The activated nitro group adjacent to the bromide allows for sequential functionalization, enabling the construction of diversely substituted pyridine derivatives.

Basic Information

Product Name	3-Bromo-4-Nitropyridine n-Oxide
CAS No.	1678-49-5
Molecular Formula	C5H3BrN2O3
Molecular Weight	218.99 g/mol
Synonyms	3-Bromo-4-nitropyridine 1-oxide; 4-Nitro-3-bromopyridine N-oxide; 3-Bromo-4-nitropyridine N-oxide; Pyridine, 3-bromo-4-nitro-, 1-oxide; 3-Bromo-4-nitropyridine oxide; 3-Br-4-NO2-Pyridine N-oxide
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Nitropyridine n-Oxide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.