Description

1,1-Difluoroethyl Isocyanate is a highly reactive fluorinated isocyanate building block, essential for introducing the difluoroethyl moiety into advanced molecular architectures. Its primary value lies in enabling the synthesis of novel compounds with enhanced metabolic stability, lipophilicity, and biological activity. This specialty chemical is critically needed by research and development teams in the pharmaceutical and agrochemical industries for creating next-generation active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in medicinal chemistry for introducing fluorine atoms to modulate pharmacokinetic properties.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the difluoroethyl group can improve efficacy and environmental profile.
• Polymer Modification: Serves as a functional monomer or cross-linking agent for creating specialty polyurethanes and polymers with unique surface properties or fluorinated characteristics.
• Liquid Crystal & Electronic Materials: Employed in the synthesis of fluorinated components for high-performance display materials and electronic chemicals.
• Chemical Research & Development: A versatile reagent in organic synthesis laboratories for constructing complex molecules and exploring new chemical entities.
• Crop Protection Agent Development: Integral to creating innovative active ingredients with improved resistance management and selectivity.

Basic Information

Product Name	1,1-Difluoroethyl Isocyanate
CAS No.	1645-88-1
Molecular Formula	C3H3F2NO
Molecular Weight	107.06 g/mol
Synonyms	1,1-Difluoroethyl isocyanate; 1,1-Difluoroethanoyl isocyanate; Isocyanic acid, 1,1-difluoroethyl ester; 2,2-Difluoroethyl isocyanate; NSC 5185; 1,1-Difluoroethylisocyanate; 1,1-Difluoroethan-1-isocyanate; α,α-Difluoroethyl isocyanate
EINECS	Contact for details

Quality Control

Every batch of 1,1-Difluoroethyl Isocyanate is manufactured and tested under strict quality management protocols to ensure consistency and purity for demanding synthetic applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and reactive nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C for extended stability. Keep away from moisture, strong bases, and any source of heat or ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.