Description

Pentafluorophenyl Isocyanate 97 is a highly reactive and versatile fluorinated aromatic isocyanate building block. Its unique perfluorinated aromatic ring confers exceptional electron-withdrawing properties, making it a critical reagent for synthesizing advanced materials and bioactive compounds with enhanced stability and performance. This high-purity grade is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries seeking to incorporate fluorine chemistry into their products.

Application

• Pharmaceutical Intermediates: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of protease inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the pentafluorophenyl group improves lipophilicity and environmental stability.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for creating high-performance polyurethanes, polyureas, and other specialty polymers with unique surface properties.
• Derivatization Reagent: Employed in analytical chemistry and proteomics for labeling amines, alcohols, and other nucleophiles to enhance detection sensitivity in chromatography and mass spectrometry.
• Liquid Crystal & OLED Materials: A precursor for synthesizing fluorinated components used in electronic displays and organic light-emitting diodes (OLEDs).
• Covalent Organic Frameworks (COFs): Acts as a linker molecule in the construction of porous, crystalline COF materials for gas storage and catalysis.

Basic Information

Product Name	Pentafluorophenyl Isocyanate 97
CAS No.	1591-95-3
Molecular Formula	C7F5NO
Molecular Weight	221.08 g/mol
Synonyms	Pentafluorophenyl isocyanate; Perfluorophenyl isocyanate; Isocyanic acid, pentafluorophenyl ester; 2,3,4,5,6-Pentafluorophenyl isocyanate; PFPI; C6F5NCO; NSC 5188
EINECS	216-456-9

Quality Control

Our Pentafluorophenyl Isocyanate 97 is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability. Each lot undergoes comprehensive analytical testing, including assay by GC/HPLC and impurity profiling, to meet the specified purity grade. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support compliance with global regulatory frameworks, including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at 2-8°C under an inert atmosphere (e.g., nitrogen or argon). Due to its highly volatile and moisture-sensitive nature, the container should be allowed to reach room temperature before opening to prevent moisture ingress and pressure buildup. Keep away from strong bases, amines, alcohols, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC/HPLC)	≥ 97.0%
Water Content (Karl Fischer)	≤ 0.1%
Density (at 20°C)	~1.6 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.