Description

2-Pentafluorophenyl-Malonic Acid Diethyl Ester is a high-purity fluorinated organic building block essential for advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals, agrochemicals, and specialty materials, where the introduction of a pentafluorophenyl group can dramatically alter biological activity and material properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and pesticides, where the fluorine atoms enhance lipophilicity and metabolic stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial labs for method development, catalysis studies, and the creation of novel fluorinated compound libraries.
• Ligand and Catalyst Design: Useful for constructing sophisticated ligands in asymmetric catalysis and organometallic chemistry due to its malonate ester functionality.

Basic Information

Product Name	2-Pentafluorophenyl-Malonic Acid Diethyl Ester
CAS No.	1582-05-4
Molecular Formula	C₁₃H₁₁F₅O₄
Molecular Weight	326.22 g/mol
Synonyms	Diethyl 2-(Pentafluorophenyl)malonate; Diethyl (Pentafluorophenyl)malonate; Pentafluorophenylmalonic Acid Diethyl Ester; 2-(Perfluorophenyl)malonic Acid Diethyl Ester; Ethyl 2-(Pentafluorophenyl)malonate; C13H11F5O4; Malonic acid, 2-(pentafluorophenyl)-, diethyl ester
EINECS	Contact for details

Quality Control

Our 2-Pentafluorophenyl-Malonic Acid Diethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.