Description

Phosphoramidemustard is a specialized organophosphorus compound of significant interest in advanced chemical research and development. Its unique molecular structure makes it a valuable intermediate for synthesizing complex bioactive molecules and novel chemical entities. This product is primarily utilized by pharmaceutical research organizations, agrochemical developers, and academic institutions engaged in medicinal chemistry and targeted synthesis programs.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of potential therapeutic agents, particularly in oncology and targeted drug discovery.
• Medicinal Chemistry Research: Used as a core scaffold or reactive moiety for structure-activity relationship (SAR) studies and lead optimization.
• Bioconjugate Development: Employed in the creation of antibody-drug conjugates (ADCs) and other targeted delivery systems due to its reactive functional groups.
• Agrochemical Synthesis: Intermediate in the development of novel pesticides and herbicides with specific modes of action.
• Chemical Biology Probes: Serves as a warhead or labeling agent in the design of activity-based probes for studying enzyme function.
• Academic & Institutional R&D: Fundamental research tool in universities and government labs studying phosphorous chemistry and alkylating agents.

Basic Information

Product Name	Phosphoramidemustard
CAS No.	1566-15-0
Molecular Formula	C7H18Cl2N2O2P
Molecular Weight	279.11 g/mol
Synonyms	N,N-Bis(2-chloroethyl)phosphoramide mustard; Phosphoramide mustard; N,N-Bis(2-chloroethyl)phosphorodiamidic acid; Cyclophosphamide metabolite; Nor-nitrogen mustard phosphoramide; PM
EINECS	Contact for details

Quality Control

Every batch of Phosphoramidemustard is manufactured and tested under a strict quality management system to ensure consistency and reliability for research applications. Our products undergo rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C to minimize oxidation and hydrolysis. Due to its hygroscopic and light-sensitive nature, the container should be allowed to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.