Description

2-Bromo-3-Fluoropropionic Acid Methyl Ester is a versatile fluorinated building block essential for advanced organic synthesis. This compound is valued for its bifunctional reactivity, offering both an electrophilic bromine and an ester group for further transformations. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the construction of complex molecules. Its unique structure makes it a key intermediate in the development of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of fluorinated active pharmaceutical ingredients (APIs) and potential drug candidates.
• Agrochemical Research: Used in the development of novel herbicides, pesticides, and fungicides that incorporate fluorine for enhanced activity and stability.
• Liquid Crystal & OLED Material Synthesis: Serves as a precursor for fluorinated components in electronic display and lighting materials.
• Peptide & Protein Modification: Employed to introduce fluorinated alkyl chains or labels into biomolecules for research and diagnostic purposes.
• Cross-Coupling Reactions: Acts as an electrophilic partner in various metal-catalyzed coupling reactions to form carbon-carbon bonds.
• Polymer Chemistry: A monomer or modifier for creating specialty fluoropolymers with unique surface properties and chemical resistance.

Basic Information

Product Name	2-Bromo-3-Fluoropropionic Acid Methyl Ester
CAS No.	1537-52-6
Molecular Formula	C4H6BrFO2
Molecular Weight	185.00 g/mol
Synonyms	Methyl 2-bromo-3-fluoropropionate; 3-Fluoro-2-bromopropionic acid methyl ester; 2-Bromo-3-fluoropropanoic acid methyl ester; Methyl 3-fluoro-2-bromopropanoate; Propanoic acid, 2-bromo-3-fluoro-, methyl ester; Bromofluoropropionic acid methyl ester
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Fluoropropionic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density	~1.65 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.