Description

Methyl 4-(Chloroformyl)Butyrate is a versatile bifunctional organic intermediate, combining both an ester and an acid chloride group in its molecular structure. This compound is highly valued for its reactivity, serving as a crucial building block for the synthesis of more complex molecules. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing active pharmaceutical ingredients (APIs), advanced materials, and fine chemicals.

Application

• Pharmaceutical Synthesis: A key precursor in the production of active pharmaceutical ingredients (APIs), particularly for constructing lactam and heterocyclic ring systems.
• Agrochemical Intermediates: Used in the synthesis of advanced herbicides, fungicides, and plant growth regulators.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for creating specialty polymers, coatings, and functionalized materials.
• Peptide Mimetics & Linkers: Employed in medicinal chemistry for the synthesis of peptide analogs and bioconjugation linkers.
• Fine Chemical Production: Acts as a versatile building block for synthesizing complex esters, amides, and other high-value specialty chemicals.
• Research & Development: Utilized in academic and industrial R&D labs for method development and exploring novel synthetic pathways.

Basic Information

Product Name	Methyl 4-(Chloroformyl)Butyrate
CAS No.	1501-26-4
Molecular Formula	C6H9ClO3
Molecular Weight	164.59 g/mol
Synonyms	4-(Chloroformyl)butyric Acid Methyl Ester; Methyl 5-Chloro-5-oxopentanoate; 5-Chloro-5-oxopentanoic Acid Methyl Ester; Glutaric Acid Chloromethyl Ester; Methyl 4-Chlorocarbonylbutyrate; Methyl γ-Chlorocarbonylbutyrate; Methyl Glutaryl Chloride; Adipic Acid Monomethyl Ester Chloride
EINECS	216-110-9

Quality Control

Our Methyl 4-(Chloroformyl)Butyrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (IR, NMR), to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support cGMP and ISO standards for production where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; therefore, it must be kept under an inert atmosphere (e.g., nitrogen or argon) and away from incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.