Description

5-Pyridin-4-Yl-4H-[1,2,4]Triazole-3-Thiol is a heterocyclic organic compound featuring a triazole-thiol core linked to a pyridine ring, serving as a versatile and high-value synthetic intermediate. This compound is critical for research and development in advanced organic synthesis, particularly for constructing complex molecular architectures. It is primarily sought after by pharmaceutical R&D laboratories, agrochemical innovators, and academic institutions for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or acting as metal chelators.
• Agrochemical Research: Used in developing new active ingredients for crop protection products, leveraging its heterocyclic structure for bioactivity.
• Ligand in Coordination Chemistry: The thiol and nitrogen donor atoms make it a valuable ligand for creating metal complexes with catalytic or diagnostic properties.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the development of advanced polymers and functional materials.
• Chemical Biology Probe: Utilized in biochemical research to study enzyme interactions or for protein labeling due to its reactive thiol group.

Basic Information

Product Name	5-Pyridin-4-Yl-4H-[1,2,4]Triazole-3-Thiol
CAS No.	1477-24-3
Molecular Formula	C7H6N4S
Molecular Weight	178.22 g/mol
Synonyms	4-(3-Mercapto-1H-1,2,4-triazol-5-yl)pyridine; 5-(4-Pyridyl)-4H-1,2,4-triazole-3-thiol; 3H-1,2,4-Triazole-3-thione, 4,5-dihydro-5-(4-pyridinyl)-; 5-(Pyridin-4-yl)-1H-1,2,4-triazole-3-thiol; 5-(4-Pyridinyl)-1,2,4-triazole-3-thiol; 4-(3-Sulfanyl-1H-1,2,4-triazol-5-yl)pyridine
EINECS	Contact for details

Quality Control

Our 5-Pyridin-4-Yl-4H-[1,2,4]Triazole-3-Thiol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and reliability for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.