Description

Methyl (R)-3-Phenylbutyrate is a chiral ester compound of significant interest in fine chemical synthesis. Its primary value lies in its role as a versatile chiral building block and intermediate for the production of optically active pharmaceuticals and agrochemicals. This high-purity enantiomer is essential for research and manufacturing processes where stereochemical control is critical. Key industries that require this material include pharmaceutical development, advanced organic synthesis, and fragrance chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs) requiring the (R)-configuration.
• Asymmetric Synthesis: Used as a starting material or resolving agent in catalytic asymmetric reactions to construct complex molecular architectures.
• Agrochemical Research: Serves as a precursor in the development of chiral pesticides and herbicides where specific enantiomer activity is desired.
• Flavor and Fragrance Ingredient: Employed in the synthesis of ester-based aromatic compounds for high-value fragrance formulations.
• Organic Chemistry Research: A valuable standard and reagent in academic and industrial laboratories studying ester chemistry and chirality.
• Liquid Crystal & Advanced Material Precursor: Potential use in the synthesis of chiral dopants and organic electronic materials.

Basic Information

Product Name	Methyl (R)-3-Phenylbutyrate
CAS No.	1472-07-7
Molecular Formula	C11H14O2
Molecular Weight	178.23 g/mol
Synonyms	(R)-Methyl 3-phenylbutyrate; (R)-3-Phenylbutyric acid methyl ester; Methyl (R)-(-)-3-phenylbutyrate; (R)-(-)-Methyl 3-phenylbutanoate; (R)-3-Phenylbutanoic acid methyl ester; β-Methylhydrocinnamic acid methyl ester, (R)-form; (R)-β-Methylbenzenepropanoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl (R)-3-Phenylbutyrate is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Refractive Index (n20D)	1.495 - 1.505
Specific Rotation ([α]20D)	-20° to -25° (c=1 in CHCl3)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.