Description

8-Benzyl-2,8-Diaza-Spiro[4.5]Decane-1,3-Dione(Hcl) CAS NO 1468-23-1 is a high-purity, nitrogen-containing spirocyclic compound primarily utilized as a sophisticated pharmaceutical intermediate. Its unique spiro[4.5]decane scaffold makes it a valuable building block for medicinal chemistry research and the synthesis of complex active pharmaceutical ingredients (APIs). This compound is essential for R&D chemists and manufacturers in the pharmaceutical and fine chemical sectors seeking to develop novel therapeutic agents, particularly in central nervous system (CNS) and other targeted drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its constrained, three-dimensional spirocyclic structure.
• API Synthesis: Serves as a critical precursor in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Employed in the development of molecular probes for studying biological pathways and protein interactions.
• Fine Chemical Production: Used in the manufacture of other high-value, specialized fine chemicals and advanced materials.
• Contract Research & Development (CRO/CMO): Supplied to research organizations and contract manufacturers for custom synthesis projects.

Basic Information

Product Name	8-Benzyl-2,8-Diaza-Spiro[4.5]Decane-1,3-Dione(Hcl)
CAS No.	1468-23-1
Molecular Formula	C15H19N2O2 • HCl
Molecular Weight	296.79 g/mol (HCl salt)
Synonyms	8-Benzyl-2,8-diazaspiro[4.5]decane-1,3-dione hydrochloride; 1,3-Dioxo-8-benzyl-2,8-diazaspiro[4.5]decane hydrochloride; 8-Benzyl-2,8-diazaspiro[4.5]decane-1,3-dione HCl; 2,8-Diaza-8-benzylspiro[4.5]decane-1,3-dione hydrochloride; Spirocyclic diketopiperazine derivative; 8-Benzyl-1,3-dioxo-2,8-diazaspiro[4.5]decane hydrochloride
EINECS	Contact for details

Quality Control

Our 8-Benzyl-2,8-Diaza-Spiro[4.5]Decane-1,3-Dione(Hcl) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications. Our quality protocols are designed to meet the stringent requirements of pharmaceutical R&D and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.