Description

n-Acetyl-L-Glutamic Acid Diethyl Ester is a high-purity, protected derivative of the amino acid L-glutamic acid. This compound serves as a critical building block (synthon) in organic synthesis, particularly for the preparation of complex peptides and pharmaceutical intermediates. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality raw materials for advanced synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used in proteomics and enzymology studies as a substrate or a protected amino acid derivative.
• Peptide Synthesis: Serves as a protected glutamic acid residue in solid-phase and solution-phase peptide synthesis (SPPS).
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, chiral auxiliaries, and complex organic molecules.
• Agrochemical Development: Potential intermediate in the research and synthesis of novel crop protection agents.

Basic Information

Product Name	n-Acetyl-L-Glutamic Acid Diethyl Ester
CAS No.	1446-19-1
Molecular Formula	C11H19NO5
Molecular Weight	245.27 g/mol
Synonyms	N-Acetyl-L-glutamic Acid Diethyl Ester; Diethyl N-Acetyl-L-glutamate; L-Glutamic Acid, N-Acetyl-, Diethyl Ester; Ac-Glu(OEt)-OEt; N-Acetylglutamic Acid Diethyl Ester; (2S)-2-Acetamidopentanedioic Acid Diethyl Ester; N-Acetyl-L-glutamic Acid Ethyl Ester
EINECS	215-898-9

Quality Control

Our n-Acetyl-L-Glutamic Acid Diethyl Ester is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical research and synthesis. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). The product may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-Isomer)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.