Description

(2R,5S)-4,4'Aα,5,5',6',7',8',8'A-Octahydro-2',5,5',5',8'Aβ-Pentamethylspiro[Furan-2(3H),1'(4'H)-Naphthalene]-5-Acetic Acid CAS NO 1438-57-9 is a high-purity, stereochemically defined spirocyclic compound with a complex fused ring structure. This compound serves as a critical chiral intermediate and building block in advanced organic synthesis, valued for its unique three-dimensional architecture. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in complex molecule synthesis.
• Asymmetric Catalysis Research: Used as a ligand precursor or a model substrate in the study and development of new stereoselective catalytic reactions.
• Agrochemical Synthesis: Serves as a sophisticated building block in the creation of advanced, biologically active compounds for crop protection.
• Material Science Research: Investigated for its potential in creating novel organic frameworks or polymers with specific structural properties.
• Academic & Industrial R&D: Employed in methodological studies and process chemistry development due to its challenging and intricate molecular scaffold.

Basic Information

Product Name	(2R,5S)-4,4'Aα,5,5',6',7',8',8'A-Octahydro-2',5,5',5',8'Aβ-Pentamethylspiro[Furan-2(3H),1'(4'H)-Naphthalene]-5-Acetic Acid
CAS No.	1438-57-9
Molecular Formula	C23H34O3
Molecular Weight	358.52 g/mol
Synonyms	Labd-8(20)-en-15-oic acid, 13,14-didehydro-, (13S)-; (13S)-Labda-8(20),13-dien-15-oic acid; (2R,5S)-4,4'Aα,5,5',6',7',8',8'A-Octahydro-2',5,5',5',8'Aβ-pentamethylspiro[furan-2(3H),1'(4'H)-naphthalene]-5-acetic acid; 8(20),13-Labdadien-15-oic acid; (13S)-8(20),13-Labdadien-15-oic acid; Abietic acid derivative; Spiro[Furan-2(3H),1'(4'H)-Naphthalene] acetic acid derivative
EINECS	Contact for details

Quality Control

Our (2R,5S)-4,4'Aα,5,5',6',7',8',8'A-Octahydro-2',5,5',5',8'Aβ-Pentamethylspiro[Furan-2(3H),1'(4'H)-Naphthalene]-5-Acetic Acid is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. All materials are characterized using advanced analytical techniques including HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles is provided with each shipment to support your R&D and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.