Description

trans-2-Amino-Cyclohexanecarboxylic Acid Ethyl Ester is a chiral, non-proteinogenic amino acid derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its rigid cyclohexane backbone and functionalized amine and ester groups, enabling the construction of complex, stereodefined molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and chiral ligands.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of peptide mimetics, enzyme inhibitors, and other bioactive molecules with constrained geometries.
• Agrochemical Research: Building block for developing novel herbicides, fungicides, and plant growth regulators with enhanced stereoselectivity.
• Asymmetric Catalysis: Used in the preparation of chiral auxiliaries, ligands, and organocatalysts for stereoselective transformations.
• Peptidomimetics & Drug Discovery: Incorporates conformational restraint into peptide chains to improve metabolic stability, bioavailability, and receptor selectivity.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes to study enzyme mechanisms and protein-protein interactions.
• Material Science: Potential monomer for synthesizing novel polyamides or other specialty polymers with unique thermal and mechanical properties.

Basic Information

Product Name	trans-2-Amino-Cyclohexanecarboxylic Acid Ethyl Ester
CAS No.	1436-61-9
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	Ethyl trans-2-aminocyclohexanecarboxylate; trans-2-Amino-1-cyclohexanecarboxylic Acid Ethyl Ester; (1R,2S)-rel-2-Aminocyclohexanecarboxylic Acid Ethyl Ester; Ethyl (1R,2S)-2-aminocyclohexane-1-carboxylate; 2-Aminocyclohexanecarboxylic Acid Ethyl Ester (trans); trans-2-Aminocyclohexane-1-carboxylic Acid Ethyl Ester; Ethyl 2-aminocyclohexanecarboxylate (trans)
EINECS	Contact for details

Quality Control

Our trans-2-Amino-Cyclohexanecarboxylic Acid Ethyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high chemical purity and consistent enantiomeric excess, meeting the stringent requirements for research and process development. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% (trans isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.