Description

(1R,2R)-2-Amino-Cyclohexanecarboxylic Acid Ethyl Ester is a high-purity chiral building block of significant importance in asymmetric synthesis. This compound is valued for its rigid cyclohexane backbone and functionalized amino and ester groups, which enable the stereoselective construction of complex molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of peptidomimetics, protease inhibitors, and other biologically active compounds.
• Asymmetric Catalyst Ligand Precursor: Used in the preparation of chiral ligands for transition metal catalysis in enantioselective reactions.
• Agrochemical Research: Serves as a building block for developing novel, stereospecific herbicides, fungicides, and plant growth regulators.
• Academic & R&D Laboratories: Employed in methodological studies and the discovery of new synthetic routes in organic chemistry.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing custom fine chemicals for clients.

Basic Information

Product Name	(1R,2R)-2-Amino-Cyclohexanecarboxylic Acid Ethyl Ester
CAS No.	1436-60-8
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	Ethyl (1R,2R)-2-aminocyclohexanecarboxylate; (1R,2R)-2-Amino-1-cyclohexanecarboxylic Acid Ethyl Ester; L-2-Aminocyclohexanecarboxylic Acid Ethyl Ester (trans); trans-2-Aminocyclohexanecarboxylic Acid Ethyl Ester; (1R,2R)-ACCA-OEt; Ethyl trans-2-aminocyclohexane-1-carboxylate
EINECS	Contact for details

Quality Control

Our (1R,2R)-2-Amino-Cyclohexanecarboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) and standard purity assays. Certificates of Analysis (COA) detailing identity, purity, and chiral purity are provided to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.