Description

6-Fluoronicotinic Acid Methyl Ester is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and material science industries seeking to introduce fluorine and nicotinate motifs into their target structures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where the fluorine atom can enhance biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic systems and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced organic electronic materials and liquid crystals.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules in research settings to study biological processes.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	6-Fluoronicotinic Acid Methyl Ester
CAS No.	1427-06-1
Molecular Formula	C7H6FNO2
Molecular Weight	155.13 g/mol
Synonyms	Methyl 6-fluoronicotinate; 6-Fluoropyridine-3-carboxylic acid methyl ester; 3-Carbomethoxy-2-fluoropyridine; 2-Fluoro-3-pyridinecarboxylic acid methyl ester; 6-Fluoro-3-pyridinecarboxylic acid methyl ester; Methyl 6-fluoro-3-pyridinecarboxylate; 6-Fluoro-nicotinic acid methyl ester
EINECS	Contact for details

Quality Control

Our 6-Fluoronicotinic Acid Methyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications. Our quality commitment supports applications requiring material for GLP research, pre-clinical studies, and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.