Description

16-α-Methylprogesterone is a synthetic progestogen, a derivative of progesterone with a methyl group at the 16-alpha position. This structural modification enhances its metabolic stability and potency, making it a valuable intermediate in the synthesis of more complex steroidal pharmaceuticals. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of hormonal therapies and novel steroid-based compounds. The compound is supplied with a focus on high purity and batch-to-batch consistency to support critical R&D and production processes.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of advanced steroidal drugs and progestogenic agents.
• Hormone Research: Used in biochemical and pharmacological studies to investigate progestogen receptor activity and steroid hormone pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• API Development: Employed in the research and development of new Active Pharmaceutical Ingredients (APIs) with targeted hormonal activity.
• Veterinary Pharmaceuticals: Potential use in developing hormonal treatments for animal health applications.

Basic Information

Product Name	16-α-Methylprogesterone
CAS No.	1239-79-8
Molecular Formula	C22H32O2
Molecular Weight	328.49 g/mol
Synonyms	16α-Methylprogesterone; 16α-Methyl-4-pregnene-3,20-dione; 16-Methylprogesterone; 16α-Methylpregn-4-ene-3,20-dione; NSC 85665; 16α-Methyl-Progesterone; 16-α-Methyl-pregn-4-ene-3,20-dione
EINECS	214-983-8

Quality Control

Our 16-α-Methylprogesterone is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the stringent requirements for pharmaceutical research and development. A detailed Certificate of Analysis (COA) documenting identity, purity (typically ≥98% by HPLC), and related substances is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.