Description

3-Quinuclidinone Hydrochloride is a versatile organic salt and a key synthetic intermediate in advanced pharmaceutical chemistry. Its value lies in its rigid, bicyclic quinuclidine structure, which serves as a privileged scaffold for designing bioactive molecules with enhanced receptor binding and metabolic stability. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of complex drug candidates, particularly those targeting the central nervous system (CNS).
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its nitrogen-containing heterocyclic core.
• Chemical Research & Development: Serves as a fundamental starting material in organic synthesis for creating novel chemical libraries and exploring structure-activity relationships (SAR).
• Ligand and Catalyst Precursor: Utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Reference Standard: Employed as a high-purity analytical standard in quality control (QC) and research laboratories for method development and validation.

Basic Information

Product Name	3-Quinuclidinone Hydrochloride
CAS No.	1193-65-3
Molecular Formula	C7H11NO·HCl
Molecular Weight	161.63 g/mol
Synonyms	1-Azabicyclo[2.2.2]octan-3-one hydrochloride; Quinuclidin-3-one hydrochloride; 3-Quinuclidone hydrochloride; 3-Oxoquinuclidine hydrochloride; Tropinone analog hydrochloride; 1-Azabicyclo[2.2.2]octan-3-one, hydrochloride; 3-Ketoquinuclidine hydrochloride
EINECS	214-777-9

Quality Control

Our 3-Quinuclidinone Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets the high-purity standards required for pharmaceutical and research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to guarantee supply reliability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.