Description

Ethyl 2-Bromo-2-Cyano-Acetate is a versatile brominated cyanoacetate ester, a key building block in organic synthesis. This compound is valued for its reactive bromine and cyano functional groups, which facilitate a range of carbon-carbon bond-forming reactions. It is primarily sought after by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing complex molecules, heterocycles, and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), particularly those containing cyano and ester functionalities.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides where its reactive sites allow for the construction of complex molecular architectures.
• Organic Synthesis Building Block: Employed in Knoevenagel condensations, Michael additions, and other C-C bond formation reactions to create α-bromo-α-cyano carbonyl compounds.
• Heterocyclic Chemistry: Serves as a starting material for the construction of pyrimidines, pyridines, and other nitrogen-containing heterocycles important in medicinal and material chemistry.
• Specialty Chemical Manufacturing: Utilized in the production of dyes, pigments, and performance chemicals requiring specific bromo and cyano substituents.
• Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel chemical entities.

Basic Information

Product Name	Ethyl 2-Bromo-2-Cyano-Acetate
CAS No.	1187-46-8
Molecular Formula	C5H6BrNO2
Molecular Weight	192.01 g/mol
Synonyms	2-Bromo-2-cyanoacetic acid ethyl ester; Ethyl bromocyanoacetate; Bromocyanoacetic acid ethyl ester; Ethyl α-bromo-α-cyanoacetate; Acetic acid, 2-bromo-2-cyano-, ethyl ester; NSC 401119; Ethyl (bromocyano)acetate
EINECS	214-695-6

Quality Control

Our Ethyl 2-Bromo-2-Cyano-Acetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.