Description

16-Alpha,17-Dihydroxy-α-Methylbenzylidenedioxyprogesterone is a high-purity synthetic steroid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of novel therapeutic agents, particularly in the field of endocrinology and hormone-related therapies. It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in the development of next-generation steroid-based pharmaceuticals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel corticosteroid and progestogen analogs for therapeutic applications.
• Research & Development: Used in academic and industrial laboratories for studying steroid receptor activity, metabolism, and structure-activity relationships (SAR).
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical analysis.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for complex steroid molecules in pilot plants and manufacturing.
• Biochemical Research: Utilized in studies investigating enzyme inhibition, hormonal pathways, and metabolic processes.

Basic Information

Product Name	16-Alpha,17-Dihydroxy-α-Methylbenzylidenedioxyprogesterone
CAS No.	1179-87-9
Molecular Formula	C29H36O6
Molecular Weight	480.60 g/mol
Synonyms	16α,17-Dihydroxy-α-methylbenzylidenedioxyprogesterone; 16α,17α-[(1-Methylethylidene)bis(oxy)]-6α-methylpregn-4-ene-3,20-dione; 6α-Methyl-16α,17α-(1-methylethylidenedioxy)pregn-4-ene-3,20-dione; Medroxyprogesterone Acetate Benzylidene Derivative; 16α,17α-Isopropylidenedioxy-6α-methylprogesterone
EINECS	Contact for details

Quality Control

Our 16-Alpha,17-Dihydroxy-α-Methylbenzylidenedioxyprogesterone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis to ensure it meets stringent specifications for research and pharmaceutical use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with the agreed-upon specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.