Description

3-[3-[(α,α,α-Trifluoro-m-Tolyl)Oxy]Propyl]-3-Azaspiro[5.5]Undecane is a high-purity, specialized organic compound featuring a unique spirocyclic amine structure linked to a trifluoromethyl-substituted aromatic ether. This molecular architecture is critical for its role as a key intermediate in advanced pharmaceutical synthesis and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the life sciences sector for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-infective drug discovery programs.
• Agrochemical Research: Used in developing next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl and spirocyclic groups can enhance bioavailability and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating sophisticated ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Investigated as a monomer or additive for specialty polymers to impart unique thermal and chemical resistance properties.
• Chemical Biology Probe: Utilized in medicinal chemistry to study enzyme inhibition and receptor-ligand interactions due to its complex, three-dimensional structure.

Basic Information

Product Name	3-[3-[(α,α,α-Trifluoro-m-Tolyl)Oxy]Propyl]-3-Azaspiro[5.5]Undecane
CAS No.	1167-20-0
Molecular Formula	C20H28F3NO
Molecular Weight	355.44 g/mol
Synonyms	3-[3-[(Alpha,Alpha,α-Trifluoro-m-tolyl)oxy]propyl]-3-azaspiro[5.5]undecane; 3-(3-((3-(Trifluoromethyl)phenoxy)propyl)-3-azaspiro[5.5]undecane; 3-Azaspiro[5.5]undecane, 3-[3-[(α,α,α-trifluoro-m-tolyl)oxy]propyl]-; 3-(3-(3-(Trifluoromethyl)phenoxy)propyl)-3-azaspiro[5.5]undecane; 3-(3-(m-Trifluoromethylphenoxy)propyl)-3-azaspiro[5.5]undecane; 1167-20-0; 3-(3-(3-Trifluoromethylphenoxy)propyl)-3-azaspiro[5.5]undecane
EINECS	Contact for details

Quality Control

Our 3-[3-[(α,α,α-Trifluoro-m-Tolyl)Oxy]Propyl]-3-Azaspiro[5.5]Undecane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.