Description

2-Fluorobenzothiazole is a high-purity fluorinated heterocyclic building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of pharmaceuticals, agrochemicals, and functional materials, enabling the introduction of the benzothiazole scaffold with a strategic fluorine substituent. It is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to optimize molecular properties and develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) agents, kinase inhibitors, and anti-infectives.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the benzothiazole core contributes to biological activity.
• Material Science Research: Serves as a building block for organic light-emitting diodes (OLEDs), liquid crystals, and other advanced electronic materials.
• Chemical Biology & Proteomics: Employed in the design of activity-based probes and fluorescent tags for studying enzyme function and protein interactions.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments for high-performance applications.
• Cross-Coupling Reactions: Acts as a substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.

Basic Information

Item	Detail
Product Name	2-Fluorobenzothiazole
CAS No.	1123-98-4
Molecular Formula	C7H4FNS
Molecular Weight	153.18 g/mol
Synonyms	2-Fluoro-1,3-benzothiazole; 2-Fluoro-benzothiazole; Benzothiazole, 2-fluoro-; 2-Fluorobenzo[d]thiazole; 2-FBT; NSC 406916; 2-Fluorobenzthiazole
EINECS	Contact for details

Quality Control

Our 2-Fluorobenzothiazole is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP starting materials and adherence to REACH regulations.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.