Description

4-Chloropyridine n-Oxide is a versatile halogenated heterocyclic building block and a key intermediate in organic synthesis. Its value lies in its unique reactivity, where the electron-deficient pyridine N-oxide moiety and the chlorine substituent offer distinct sites for nucleophilic and electrophilic substitution reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, enabling the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various drug candidates, including kinase inhibitors, anti-inflammatory agents, and other bioactive heterocycles.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, where the chloropyridine structure is a common pharmacophore.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and polymers with specific electronic properties.
• Chemical Derivatization: The reactive chlorine atom allows for functionalization to create a diverse library of substituted pyridine N-oxide derivatives for screening and development.

Basic Information

Product Name	4-Chloropyridine n-Oxide
CAS No.	1121-76-2
Molecular Formula	C5H4ClNO
Molecular Weight	129.54 g/mol
Synonyms	4-Chloropyridine 1-Oxide; 4-Chloropyridine N-Oxide; 4-Chloro-1-oxidopyridin-1-ium; 4-Chloropyridine Oxide; Pyridine, 4-chloro-, 1-oxide; 1-Hydroxy-4-chloropyridinium
EINECS	214-342-5

Quality Control

Our 4-Chloropyridine n-Oxide is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.