Description

2-Amino-5-Chloropyridine is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both an amino group and a chloro substituent on the pyridine ring, makes it an indispensable intermediate for constructing complex molecular architectures. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with heterocyclic cores, such as kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and insecticides, where the chloropyridine structure contributes to biological activity.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing nitrogen-containing ligands used in coordination chemistry and catalysis.
• Material Science: Employed in the development of organic electronic materials, including charge-transport layers and light-emitting components.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring novel heterocyclic compounds and reaction pathways.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments due to its ability to form conjugated systems.

Basic Information

Product Name	2-Amino-5-Chloropyridine
CAS No.	1072-98-6
Molecular Formula	C5H5ClN2
Molecular Weight	128.56 g/mol
Synonyms	5-Chloro-2-pyridinamine; 5-Chloro-2-aminopyridine; 2-Pyridinamine, 5-chloro-; 5-Chloropyridin-2-amine; 2-Amino-5-chloropyridin; 5-Chloro-2-aminopyridin; 2-Amino-5-chloro-pyridine; 5-Chloro-2-pyridylamine
EINECS	214-008-4

Quality Control

Our 2-Amino-5-Chloropyridine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring reliable and reproducible synthetic results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong acids. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.