Description

2-Amino-5-Bromopyridine is a versatile brominated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of its amino and bromo functional groups, enabling selective cross-coupling and substitution reactions essential for constructing complex molecular architectures. This high-purity intermediate is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Preparation: Serves as a starting material for creating specialized nitrogen-containing ligands used in homogeneous catalysis.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers and light-emitting compounds.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions.
• Chemical Research & Development: A fundamental reagent for exploring new heterocyclic chemistry and synthesizing novel chemical libraries for screening.

Basic Information

Product Name	2-Amino-5-Bromopyridine
CAS No.	1072-97-5
Molecular Formula	C5H5BrN2
Molecular Weight	173.01 g/mol
Synonyms	5-Bromo-2-pyridinamine; 5-Bromo-2-aminopyridine; 2-Pyridinamine, 5-bromo-; 5-Bromopyridin-2-amine; NSC 403697; 2-Amino-5-brompyridin; 5-Bromo-2-aminopyridin; 5-Brom-2-aminopyridin
EINECS	214-003-5

Quality Control

Our 2-Amino-5-Bromopyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is light-sensitive (store away from light) and hygroscopic (moisture-sensitive). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.