Description

n-Acetyl-L-Aspartic Acid Diethyl Ester is a high-purity, protected derivative of the amino acid L-aspartic acid, serving as a critical chiral building block in advanced organic synthesis. This compound matters for its role in constructing complex peptide mimetics and active pharmaceutical ingredients (APIs) with precise stereochemistry. It is primarily needed by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries for developing novel therapeutics and biochemical tools.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of peptide-based drugs, enzyme inhibitors, and neuroactive compounds.
• Biochemical Research: Used in the study of enzyme mechanisms and as a precursor for labeled compounds in metabolic pathway analysis.
• Peptide Synthesis: Serves as a protected aspartic acid derivative in solid-phase and solution-phase peptide synthesis to prevent unwanted side reactions.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemical configurations.
• Agrochemical Development: Utilized as a building block for creating chiral active ingredients with targeted biological activity.

Basic Information

Product Name	n-Acetyl-L-Aspartic Acid Diethyl Ester
CAS No.	1069-39-2
Molecular Formula	C10H17NO5
Molecular Weight	231.25 g/mol
Synonyms	N-Acetyl-L-aspartic acid diethyl ester; Diethyl N-acetyl-L-aspartate; L-Aspartic acid, N-acetyl-, diethyl ester; Ac-Asp(OEt)-OEt; (2S)-2-Acetamidobutanedioic acid diethyl ester; N-Acetylaspartic acid diethyl ester; N-Acetyl-L-aspartic acid ethyl ester
EINECS	213-978-9

Quality Control

Our n-Acetyl-L-Aspartic Acid Diethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.