Description

8-Benzyl-3-(Hydroxymethyl)-1-Phenyl-1,3,8-Triazaspiro[4.5]Decan-4-One is a sophisticated heterocyclic organic compound featuring a unique spirocyclic core structure, making it a valuable intermediate for advanced chemical synthesis. This compound matters for its role as a critical building block in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals, where its specific molecular architecture enables precise chemical modifications. Pharmaceutical research organizations, agrochemical developers, and specialty chemical manufacturers need this high-purity intermediate to drive innovation in drug discovery and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and psychiatric disorders.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides with novel modes of action.
• Chemical Synthesis Building Block: Employed in organic chemistry research for constructing complex nitrogen-containing heterocycles and spiro compounds.
• Material Science: Investigated as a monomer or additive for creating specialty polymers with unique thermal or mechanical properties.
• Bioconjugation Chemistry: The hydroxymethyl group provides a handle for linking to other molecules, useful in probe and diagnostic agent development.
• Academic & Industrial R&D: Serves as a standard or reference compound in methodological studies and catalysis research.

Basic Information

Product Name	8-Benzyl-3-(Hydroxymethyl)-1-Phenyl-1,3,8-Triazaspiro[4.5]Decan-4-One
CAS No.	1050-51-7
Molecular Formula	C21H25N3O2
Molecular Weight	351.45 g/mol
Synonyms	1-Phenyl-8-benzyl-3-(hydroxymethyl)-1,3,8-triazaspiro[4.5]decan-4-one; 8-Benzyl-3-hydroxymethyl-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one; 1,3,8-Triazaspiro[4.5]decan-4-one, 8-benzyl-3-(hydroxymethyl)-1-phenyl-; Spiro[1,3,8-triazaspiro[4.5]decan-4-one, 8-benzyl-3-(hydroxymethyl)-1-phenyl- derivative; CAS 1050-51-7; 1050-51-7; Benzyl-Phenyl-Triazaspirodecanoine Hydroxymethyl Derivative
EINECS	Contact for details

Quality Control

Our 8-Benzyl-3-(Hydroxymethyl)-1-Phenyl-1,3,8-Triazaspiro[4.5]Decan-4-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Production adheres to current Good Manufacturing Practices (cGMP) where applicable, and all materials are supported by comprehensive analytical documentation. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.